Searchable abstracts of presentations at key conferences in endocrinology

ea0081p512 | Late-Breaking | ECE2022

Changes in acromegaly presentation and treatment over a three-decade period

Aagaard Charlotte , S Christophersen Amanda , Finnerup Susanne , Rosendal Christian , Vestergaard Peter , Karmisholt Jesper , H Nielsen Eigil , Dal Jakob

Objective: To study time-dependent changes in the prevalence and patient characteristics of acromegaly, as well as to access the impact of changes in treatment on disease control.Methods: A total of 107 patients with acromegaly were identified by healthcare registries and subsequently validated by patient chart review over a three-decade period (1992-2021).Results: The prevalence of acromegaly significantly increased throughout the...

ea0090p405 | Pituitary and Neuroendocrinology | ECE2023

The TRH test is a valuable diagnostic test in central hypothyroidism with low T4

Norma Smith* Liv , Ellegaard Christensen* Sara , Rosendal Christian , Angela Gulisano Helga , Ettrup Kare , H Nielsen Eigil , Karmisholt Jesper , Dal Jakob

Objective: To evaluate the value of the thyrotropin-releasing hormone (TRH) test in the diagnosis of central hypothyroidism (CH) in patients with pituitary disease.Methods: Systematic evaluation of 368 TRH tests including measurements of TBG corrected thyroxine (T4corr), baseline TSH (TSH0) and fold and absolute TSH increase (TSHfold, TSHabsolute) in patients with pituitary disease.Result...

ea0090p437 | Pituitary and Neuroendocrinology | ECE2023

Acromegaly management in the Scandinavian countries – a DELPHI consensus survey

Arlien-Soborg Mai C. , Dal Jakob , Heck Ansgar , Stochholm Kirstine , H Nielsen Eigil , Feltoft Claus , Krogh Rasmussen AEse , Feldt-Rasmussen Ulla , Andreassen Mikkel , Klose Marianne , Leo Nielsen Torben , Andersen Marianne , Lehmann Christensen Louise , Krogh Jesper , Jarlov Anne , Lyngvi Fougner Stine , Nermoen Ingrid , Bollerslev Jens , Oksnes Marianne , Dahlqvist Per , Olsson Tommy , Berinder Katarina , Hoybye Charlotte , Petersson Maria , AEkerman Anna-Karin , Wahlberg Jeanette , Ekman Bertil , Eden Engstrom Britt , Johannsson Gudmundur , Ragnarsson Oskar , Agusta Sigurjonsdottir Helga , Burman Pia , Otto Jorgensen Jens

Background: Acromegaly is associated with increased morbidity and mortality if left untreated. The therapeutic options include surgery, medical treatment, and radiotherapy. Guidelines regarding treatment algorithms and follow-up vary considerably.Aim: To evaluate consensus on the treatment and follow-up of acromegaly in the Scandinavian countries.Methods: To map the landscape of acromegaly management in the Scandinavian countries, ...